5-Amino-1-methylquinolinium chloride CAS No.:42464-96-0 98.0% purity min. | supplement ingredients manufacturer
Product Parameters
| Product name | 5-Amino-1-methylquinolinium chloride（5-amino-1MQ） |
| Other name | 5-amino-1MQ5-Amino-1-mq chloride
5-Amino-1-methylquinolinium chloride 5-Amino-1-methylquinolin-1-ium chloride 5-AMINO-1-METHYLQUINOLIN-1-IUM CHLOEIDE 5-Amino-1-methyl-1-quinolinium chloride |
| CAS No. | 42464-96-0 |
| Molecular formula | C₁₀H₁₁ClN₂ |
| Molecular weight | 194.6 |
| Purity | 98% |
| Appearance | Brown to reddish brown solid |
| Packing | 1kg/bag, 25kg/barrel |
| Application | Dietary Supplement Raw Material |
Product introduction
5-Amino-1-methylquinolinium chloride is an enzyme overexpressed during skeletal muscle aging and is associated with repair of NAD+ pathway damage, dysregulated sirtuin1 activity, and increased muscle stem cell senescence. 5-Amino-1-methylquinolinium chloride promotes myoblast differentiation in vitro and enhances fusion and regeneration of muscle stem cells in aged mice. 5-Amino-1-methylquinolinium chloride is also a potent inhibitor of nicotinamide N-methyltransferase (NNMT), selectively binding to NNMT substrate binding site residues. 5-Amino-1-methylquinolinium chloride promotes myoblast differentiation in vitro and enhances fusion and regeneration of muscle stem cells in aged mice. Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism.
5-Amino-1-Methylquinolinium Chloride works within your microbiome to reduce adipose (fat) tissue and help you lose weight.When extra fat cells accumulate, your body overproduces an enzyme known as NNMT (nicotinamide N-methyltransferase). The more NNMT, the more your body increases inflammation and stores fat. 5-Amino-1-Methylquinolinium Chloride inhibits NNMT, allowing your body to drop excess weight.
Feature
(1) High purity: 5-Amino-1-methylquinolinium chloride can obtain high-purity products through refined production processes. High purity means better bioavailability.
(2) Targeting: 5-Amino-1-methylquinolinium chloride specifically targets the NNMT enzyme and can effectively inhibit its activity, thereby affecting the metabolic pathway of nicotinamide.
(3) Stability: 5-Amino-1-methylquinolinium chloride has good stability and can maintain its activity and effect under different environments and storage conditions.
(4) Development prospects: Due to the various characteristics of NNMT, its development has received widespread attention and has broad research and application prospects.
Applications
5-Amino-1-methylquinolinium chloride is a nicotinamide N-methyltransferase (NNMT) inhibitor that promotes myoblast differentiation. 5-Amino-1-methylquinolinium chloride can also be used as a supplement to help reduce weight and fat and improve liver fat.
