Calcium Alpha-Ketoglutarate is an important biological compound widely used in nutritional supplements and sports nutrition. Its CAS number is 71686-01-6 and its purity is usually 99%. This compound is involved in many metabolic processes in the body, especially in energy production and amino acid synthesis.
Calcium Alpha-Ketoglutarate plays an important physiological role in the human body. It is an intermediate in the tricarboxylic acid cycle (TCA cycle) and is involved in energy metabolism. In addition, Calcium Alpha-Ketoglutarate is also believed to have antioxidant properties, which helps to reduce exercise-induced oxidative stress and promote muscle recovery. Therefore, it has received widespread attention in sports nutrition, anti-aging and overall health.
Calcium alpha-ketoglutarate (Ca-AKG) is a stabilized form of alpha-ketoglutarate, a naturally occurring compound in the body that plays a key role in energy production, cellular health, and metabolism.
As we age, the body’s production of AKG decreases significantly, making supplementation a potential way to address some of the effects of aging.
In its natural form, AKG supports cell renewal and helps power various body processes during growth and recovery. It also plays a role in protein synthesis and supports digestion and kidney function.
However, by the time we reach our 80s, AKG levels in our bodies are only 10% of what they were at 40, making supplementation an interesting option for those looking to stay healthy as they age.
The calcium-stabilized version, Ca-AKG, increases the bioavailability of the compound and ensures it can be absorbed more efficiently by the body.
This makes it a practical way to harness the benefits of AKG, which studies suggest may help improve overall health and reduce frailty in older adults.
Calcium alpha-ketoglutarate (Ca-AKG) is a salt form of alpha-ketoglutaric acid, a key organic acid involved in the Krebs cycle. This metabolic pathway is essential for energy production, as it is responsible for converting nutrients into ATP (adenosine triphosphate), the energy currency of cells. Ca-AKG plays a pivotal role in this process, facilitating the efficient transfer of energy and contributing to overall cellular health.
Produced both naturally within the body and available as a dietary supplement, Ca-AKG’s significance extends beyond energy metabolism. It acts as an important molecular player in various physiological processes, including amino acid synthesis and nitrogen transport. Its supplemental form is often sought after for its purported health benefits, ranging from enhanced longevity to improved physical performance.
Supporting Bone Health
Ca-AKG plays a key role in keeping our bones strong and healthy because it helps our bodies use calcium more effectively. Calcium is a vital mineral for bone strength, and Ca-AKG makes it easier for our bodies to absorb this important nutrient. Research has shown that Ca-AKG supplements can be particularly beneficial for preventing and managing weak bones, By improving how much calcium our bones can take in, Ca-AKG not only helps increase the density of our bones but also slows down the rate at which our bones break down or lose mass. This means stronger bones that are less likely to fracture or become weak over time.
Energy Production and Fatigue Reduction
Ca-AKG is at the heart of how our bodies create energy. It plays a vital role in the Krebs cycle, which is a major process for making energy inside our cells. Ca-AKG helps turn the food we eat into adenosine triphosphate (ATP), which is like fuel for our cells. This process is especially important for parts of our body that need a lot of energy, like our heart and muscles. By helping to produce more ATP, Ca-AKG can help us feel more energetic and improve our endurance, making it easier to stay active and healthy.
May Help Reduce Inflammation
Ca-AKG may help reduce systemic inflammation by regulating cytokine production, crucial molecules in the body’s inflammatory response. This regulation is significant as chronic inflammation is linked to conditions like metabolic syndrome and diabetes. Research supports Ca-AKG’s role in lowering inflammatory markers, highlighting its potential in managing inflammation-related diseases.
Ca-AKG and longevity
One of the key functions of Ca-AKG is its participation in the process of autophagy. In simple terms, autophagy is the body’s way of removing and recycling damaged or dysfunctional cells and cell parts. This process is essential for maintaining the overall health and function of our cells, tissues, and organs.
As we age, our body’s ability to perform autophagy declines. This decline has been linked to accelerated aging and an increased risk of age-related diseases. Therefore, it is critical to support our body’s autophagy process, and Ca-AKG can play an important role in this.
In addition to its role in autophagy, Ca-AKG also activates AMP-activated protein kinase (AMPK), which is essential for maintaining cellular energy balance. This protein helps monitor and regulate energy levels in our cells, ensuring they have enough energy to perform their various functions efficiently.
By activating AMPK, Ca-AKG improves energy homeostasis and supports healthy blood sugar control – both of which play critical roles in overall health and have a direct impact on the aging process.
Brain Health
One of the most significant effects of aging is a decrease in mental acuity, which can be exacerbated by the presence of neurological disease.
AKG is a precursor to the excitatory neurotransmitter glutamate and may well play a vital role in helping older adults improve memory and neurotransmission. Additionally, AKG can reduce oxidative stress, a risk factor for several neurological diseases such as Alzheimer's and Parkinson's. This suggests that AKG supplementation may help promote brain health and reduce the chances of cognitive decline in older adults.
Ketoglutarate (α-ketoglutarate) and calcium α-ketoglutarate (calcium α-ketoglutarate) are two commonly mentioned compounds. Although their names are similar, there are significant differences in structure, function and application. This article will explore the differences between the two in depth to help readers better understand their role in the body and their potential health benefits.
Basic concept of ketoglutarate
Ketoglutaric acid is an important organic acid and an intermediate in the tricarboxylic acid cycle (TCA cycle). It plays a key role in cellular metabolism and is involved in energy production and amino acid synthesis. Ketoglutaric acid is not only a key component of energy metabolism, but also plays an important role in the redox reaction of cells. In addition, ketoglutaric acid is also believed to have antioxidant properties and can help remove free radicals in the body, thereby protecting cells from oxidative damage.
Basic concept of calcium ketoglutarate
Calcium ketoglutarate is a salt compound formed by the combination of ketoglutaric acid and calcium ions. It not only retains the biological activity of ketoglutaric acid, but also increases calcium intake. Calcium is one of the essential minerals for the human body and is involved in many physiological processes such as bone health, nerve conduction and muscle contraction. Therefore, calcium ketoglutarate is often used as a dietary supplement, especially when calcium intake needs to be increased.
Main Differences
Chemical structure: Ketoglutaric acid is a simple organic acid, while calcium ketoglutarate is a complex of it and calcium ions. The former is a single molecule, while the latter is a compound containing calcium.
Physiological function: Ketoglutaric acid is mainly involved in energy metabolism and amino acid synthesis, while calcium ketoglutarate not only has the function of ketoglutaric acid, but also provides nutritional support for calcium. For people who need calcium supplementation, calcium ketoglutarate is a more ideal choice.
Applications: Ketoglutaric acid is often used in sports nutrition and antioxidant supplements, while calcium ketoglutarate is more commonly found in bone health supplements. For athletes, ketoglutaric acid can help improve energy levels and endurance, while for the elderly or people with calcium deficiency, calcium ketoglutarate is an effective choice for calcium supplementation.
Absorption and utilization: Ketoglutaric acid is absorbed and utilized more efficiently in the body, while calcium ketoglutarate may affect the absorption of other minerals in some cases because it contains calcium. Therefore, when choosing supplements, you need to make reasonable choices based on your personal health status and needs.
In general, there are obvious differences between ketoglutaric acid and calcium ketoglutarate in terms of chemical structure, function and application. Understanding these differences can help us better choose the nutritional supplements that are suitable for us in our daily lives. Whether it is to increase energy levels or to enhance bone health, choosing the right supplement is crucial.
1. Choose a reliable supplier
When acquiring Calcium Alpha-Ketoglutarate, it is important to choose a reputable supplier. Suzhou Myland is a professional dietary supplement raw material supplier that provides high-purity Calcium Alpha-Ketoglutarate (CAS: 71686-01-6) with a purity of up to 99%. Choosing such a supplier can ensure that the product you get is of reliable quality and suitable for research or other purposes.
2. Order online
Suzhou Myland provides a convenient online ordering service. Users can browse product information through its official website and learn about the detailed specifications and uses of Calcium Alpha-Ketoglutarate. The online ordering process is usually simple and fast. Users only need to select the required product, fill in the relevant information and complete the payment.
3. Understand the laws and regulations
Before buying Calcium Alpha-Ketoglutarate, it is very important to understand the laws and regulations in the country or region you live in. Certain countries have strict restrictions on the sale and use of nutritional supplements, so before purchasing, make sure you understand the relevant legal requirements to avoid unnecessary trouble.
4. Research product information
Before purchasing, it is recommended that you carefully read the product instructions and related literature to understand the properties, uses, dosages, and potential side effects of Calcium Alpha-Ketoglutarate. This will help you make an informed decision when using it and ensure the safe and effective use of this compound.
5. Do proper research
If you are a researcher or business, it is recommended that you conduct appropriate research in a laboratory setting after acquiring Calcium Alpha-Ketoglutarate. Make sure to follow laboratory safety practices and conduct experiments under the guidance of professionals to ensure safety and effectiveness.
Calcium Alpha-Ketoglutarate is an important compound with extensive research potential and application prospects. By choosing a reliable supplier such as Suzhou Myland, users can easily obtain high-purity Calcium Alpha-Ketoglutarate. During the purchase and use process, it is important to follow relevant laws and regulations and conduct sufficient research to ensure safe and effective use. Whether for scientific research or personal use, understanding the characteristics and effects of Calcium Alpha-Ketoglutarate will help better utilize this compound to promote health and athletic performance.
Disclaimer: This article is for general information only and should not be construed as any medical advice. Some of the blog post information comes from the Internet and is not professional. This website is only responsible for sorting, formatting and editing articles. The purpose of conveying more information does not mean that you agree with its views or confirm the authenticity of its content. Always consult a health care professional before using any supplements or making changes to your health care regimen.
Post time: Mar-07-2025
