As an endogenous substance in the human body, L-α-glycerophosphocholine can penetrate the blood-brain barrier and has extremely high bioavailability. It is a high-quality nutrient that is vital to the human body. "The blood-brain barrier is a dense, 'wall'-like structure between the capillary plexuses of the brain. L-α-glycerophosphocholine can easily penetrate the blood-brain barrier and play a role in enhancing memory, improving thinking, and It has potential benefits in relieving anxiety, stabilizing mood, and increasing muscle strength and endurance. "The nutritional effects of L-α-glycerophosphocholine are mainly reflected in 5 aspects.
One is to improve brain function. The greater the number of nerve cells in the brain, the stronger their vitality, the faster they transmit nerve signals, and the stronger the brain's processing power. L-α-glycerophosphocholine can comprehensively improve brain function by enhancing the vitality of nerve cells and the transmission ability of nerve signals. In terms of enhancing cholinergic neurotransmission, signal transmission between nerve cells relies on the transmission of neurotransmitters, and acetylcholine is a key chemical messenger and neurotransmitter that ensures active thinking and maintains coordination between the brain and the whole body.
L-α-glycerophosphocholine can be decomposed into 3-glycerol phosphate and choline in the brain and is the most efficient supply of acetylcholine. It can enhance memory and improve thinking by promoting the synthesis and release of acetylcholine in the brain. In terms of enhancing the stability and fluidity of cell membranes, L-α-glycerophosphocholine can promote the synthesis of phosphoinositide, thereby enhancing the stability and fluidity of cell membranes. Neurons with intact structures can better transmit information. Improve the body's thinking agility.
The second is nutrition and nerve protection. Neurotrophic factors, growth factors of nervous tissue, can regulate stem cell differentiation and promote the formation of new neural connections. L-α-glycerophosphocholine can promote the secretion of a variety of neurotrophic factors and activate signaling pathways related to cell survival, thus It exerts a neuroprotective effect and improves the body's cognitive level. At the same time, L-α-glycerophosphocholine can also promote the secretion of growth hormone and maintain body health by increasing the body's growth hormone levels.
The third is antioxidant. Oxidation and inflammation are the main causes of aging and death of brain cells. L-α-glycerophosphocholine can scavenge free radicals in the body, fight oxidative stress, and can also reduce nuclear factor NF-κB, tumor necrosis factor TNF-α, and interleukins. The release of inflammatory factors such as IL-6 counteracts brain inflammation, thereby significantly reversing the decline of cognitive function and preventing the occurrence and development of neurodegenerative diseases.
The relevant effects have been supported by clinical effects. In the study "The Effect of L-α-glycerophosphocholine on age-related memory impairment", 4 subjects were given placebo, and the other 5 subjects were given After taking L-α-glycerophosphocholine (1200 mg/day) orally for 3 months, 16 electrodes were used to record brain waves for 5 minutes while the subjects were awake and resting. The results showed that compared to placebo, L-alpha-glycerophosphocholine significantly increased the proportion of the fastest brain waves while having a tendency to decrease the slowest frequencies. That is, it can enhance the brain vitality of middle-aged people and delay the aging of the body.
The fourth is to regulate emotions. Dopamine can make people feel happy, and serotonin and gamma-aminobutyric acid can regulate the body's mood. L-α-glycerophosphocholine can promote the release of dopamine, up-regulate the expression of dopamine transporters, improve dopamine neurotransmission in the brain, and increase the levels of serotonin in the striatum and prefrontal cortex; it can also significantly promote endogenous The release of γ-aminobutyric acid in sexual cortical tissue relieves insomnia, thus exerting its anti-depressant, anxiety-relieving and mood-stabilizing effects.
The fifth is to improve sports performance. During exercise, L-alpha-glycerophosphocholine also improves body composition by increasing muscle mass and improving overall metabolic activity by increasing acute growth hormone production and power output. In addition, L-α-glycerophosphocholine can also speed up neurotransmitter transmission, improve the efficiency of neuromuscular connections, increase the contractility and endurance of skeletal muscles, thereby enhancing the body's exercise intensity, anti-fatigue, and exerting a positive influence on muscle growth. influence.
So where can people get this nutrient with so many potential benefits? In fact, L-α-glycerophosphocholine is contained in many foods such as eggs, chicken, and rainbow trout, but the content is generally small. According to the "Second Edition of the U.S. General Food Choline Content Database" published by the United States Department of Agriculture, the content of L-α-glycerophosphocholine in a total of 630 foods in 22 categories showed that L-α-glycerophosphocholine per 100 grams of food The content of glycerophosphocholine ranges from 0 to 190 mg. Therefore, in order to meet the needs of human body growth, development and metabolism, additional supplements can be made appropriately.
Chemical synthesis is one of the main production methods of L-α-glycerophosphocholine. Using polyphosphoric acid, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide and water as raw materials, after condensation and esterification reaction, it is decolorized, impurity removed, concentrated, refined and dried. L-α-glycerophosphocholine made by other processes can be added to soft drinks, sports drinks, coffee, gummies, oatmeal energy bars, etc., and can exert its nutritional effects in a targeted manner to meet the diversified nutritional health of consumers. need.
In the United States, Japan, Canada and other countries, L-α-glycerophosphocholine has been widely used in food. Related products cover dietary supplements, beverages, gummies and other categories, and each product has a clear Functions, recommended dosage and recommended groups.
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Post time: Sep-25-2024
