What Is NAD+ and Why Do You Need It for Your Health?

In the ever-growing world of health and wellness, NAD+ has become a buzzword, attracting the attention of scientists and health enthusiasts alike. But what exactly is NAD+? Why is it so important to your health? Let’s learn more about the relevant information below!

What is NAD+?

NAD's scientific name is nicotinamide adenine dinucleotide. NAD+ exists in every cell of our body. It is a key metabolite and coenzyme in various metabolic pathways. It mediates and participates in various biological processes. More than 300 enzymes depend on NAD+ To work.

NAD+ is the English abbreviation of Nicotinamide adenine dinucleotide. Its full name in Chinese is nicotinamide adenine dinucleotide, or Coenzyme I for short. As a coenzyme that transmits hydrogen ions, NAD+ plays a role in many aspects of human metabolism, including glycolysis, Gluconeogenesis, tricarboxylic acid cycle, etc. Some studies have pointed out that the depletion of NAD+ is related to age, and the physiological mechanisms mediated by NAD+ are related to aging, metabolic diseases, neuropathy and cancer, including regulating cell homeostasis, sirtuins known as "longevity genes", repairing DNA, PARPs family proteins related to necroptosis and CD38 that assists in calcium signaling.

NAD+ acts as a shuttle bus, carrying electrons from one cell molecule to another. Together with its molecular counterpart NADH, it participates in various metabolic reactions through electron exchange that produce adenosine triphosphate (ATP), the body's "energy" molecule.

Simply put, NAD+ is crucial to maintaining body health and balance. Metabolism, redox, DNA maintenance and repair, gene stability, epigenetic regulation, etc. all require the participation of NAD+.

Therefore, our body has a high demand for NAD+. NAD+ is continuously synthesized, broken down and recycled in cells to maintain stable cellular NAD+ levels.

NAD+ is an important component of cellular activity and is involved in energy supply and DNA repair, both of which are closely related to healthy aging.

1) It is widely distributed in all cells of the human body and participates in thousands of biocatalytic reactions. It can promote the metabolism of sugar, fat and amino acids, and participate in the synthesis of energy. It is an important coenzyme necessary for the human body.

2) NAD+ is the only substrate for coI-consuming enzymes (the only substrate for the DNA repair enzyme PARP, the only substrate for the longevity protein Sirtuins, and the only substrate for the cyclic ADP ribose synthase CD38/157).

However, as age increases, the level of NAD+ in the body decreases rapidly. It will decrease by 50% every 20 years. At almost 40 years old, the NAD+ content in the human body is only 25% of what it was in children.

If human cells lack NAD+, mitochondrial dysfunction is reduced, DNA damage repair ability is reduced, and the longevity gene protein family Sirtuin is also inactivated, etc. These negative factors can lead to apoptosis, human disease, aging and even death.

The Role of NAD+ in Your Overall Health

Anti-aging

NAD+ maintains chemical communication between the nucleus and mitochondria, and weakened communication is an important cause of cellular aging.

NAD+ can remove the increasing number of erroneous DNA codes during cell metabolism, maintain the normal expression of genes, maintain the normal operation of cells, and slow down the aging of human cells.

Repair DNA damage

NAD+ is an essential substrate for the DNA repair enzyme PARP, which has a significant impact on DNA repair, gene expression, cell development, cell survival, chromosome reconstruction, and gene stability.

Activate longevity protein

Sirtuins are often called the longevity protein family and play an important regulatory role in cell functions, such as inflammation, cell growth, circadian rhythm, energy metabolism, neuronal function, and stress resistance, and NAD+ is an important enzyme for the synthesis of longevity proteins.

Activates all 7 longevity proteins in the human body, playing an important role in cellular stress resistance, energy metabolism, preventing cell mutation, apoptosis and aging.

Provide energy

It catalyzes the production of more than 95% of the energy required for life activities. Mitochondria in human cells are the power plants of cells. NAD+ is an important coenzyme in mitochondria to generate the energy molecule ATP, converting nutrients into the energy needed by the human body.

Promote blood vessel regeneration and maintain blood vessel elasticity

Blood vessels are indispensable tissues for life activities. As we age, blood vessels gradually lose their flexibility and become harder, thicker, and narrower, causing "arteriosclerosis."

NAD+ can increase the activity of elastin in blood vessels, thereby maintaining the elasticity of blood vessels and maintaining blood vessel health.

Promote metabolism

Metabolism is the sum of various chemical reactions in the body. The body will continue to exchange matter and energy. When this exchange stops, the life of the body will also end.

Professor Anthony and his research team at the University of California, USA, found that NAD+ can effectively improve the slowdown of cell metabolism associated with aging, thereby improving people's health and extending lifespan.

Protect heart health

The heart is the most important organ of human beings, and the NAD+ level in the body plays a crucial role in maintaining the normal operation of the heart.

The reduction of NAD+ may be related to the pathogenesis of many cardiovascular diseases, and a large number of basic studies have also confirmed the effect of supplementing NAD+ on heart diseases.

Prevent cardiovascular and cerebrovascular diseases

Studies have shown that almost all seven subtypes of sirtuins (SIRT1-SIRT7) are related to the occurrence of cardiovascular disease. Sirtuins are considered to be agonistic targets for the treatment of cardiovascular diseases, especially SIRT1.

NAD+ is the only substrate for Sirtuins. Timely supplementation of NAD+ to the human body can fully activate the activity of each subtype of Sirtuins, thereby protecting cardiovascular health and preventing cardiovascular diseases.

Promote hair growth

The main cause of hair loss is the loss of hair mother cell vitality, and the loss of hair mother cell vitality is because the NAD+ level in the human body decreases. The hair mother cells do not have enough ATP to carry out hair protein synthesis, thus losing their vitality and leading to hair loss.

Therefore, supplementing NAD+ can strengthen the acid cycle and produce ATP, so that the hair mother cells have enough ability to produce hair protein, thereby improving hair loss.

Where to Buy Beta-NAD+ Supplement Safely Online

Suzhou Myland Pharm & Nutrition Inc. is an FDA-registered manufacturer that provides high-quality and high-purity NAD+ Supplement powder.

At Suzhou Myland Pharm we are committed to providing the highest quality products at the best prices. Our NAD+ Supplement powder is rigorously tested for purity and potency, ensuring you get a high-quality supplement you can trust. Whether you want to support cellular health, boost your immune system or enhance overall health, our NAD+ Supplement powder is the perfect choice.

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In addition, Suzhou Myland Pharm is also an FDA-registered manufacturer. The company's R&D resources, production facilities, and analytical instruments are modern and multifunctional, and can produce chemicals from milligrams to tons in scale, and comply with ISO 9001 standards and production specifications GMP.