Urolithin A This is a natural compound produced in the gut that supports mitochondrial health and may benefit muscle function, brain, heart and skin health.
What's interesting about urolithin A is its potential beneficial effects on mitochondria, the powerhouses of cells that help the body produce energy. Since your mitochondria are key players in many of your body's functions, anything that helps them stay healthy creates a trickle-down effect that leads to many other significant benefits for your muscles, brain, heart, and overall health.
Although gut bacteria produce urolithin A when you eat certain foods, not everyone produces urolithin A. Therefore, some people choose to include urolithin A supplements in their health regimen to reap its potential benefits.
Urolithin A is a natural compound produced by gut bacteria when you eat or drink foods containing ellagitannins, a type of polyphenol. Ellagitannins occur naturally in nuts and fruits, such as pomegranates, certain berries, walnuts, and almonds.
When ellagitannins reach your small intestine, they are broken down and release a compound called ellagic acid, which your gut flora can convert into urolithins, including urolithin A.
Urolithins are postbiotics, byproducts of beneficial bacteria that feed on fiber and have many health benefits. Urolithin A is the first postbiotic discovered to stimulate mitophagy—the cleaning and recycling of mitochondria.
However, some people are unable to break down ellagitannins based on their individual metabolism. The type and amount of urolithin you produce depends on which bacteria live in your gut. In fact, one study showed that only about 40% of participants produced urolithin A after consuming pomegranate juice.
What does Urolithin A do in the body?
Mitochondria are the powerhouses of the cell, responsible for producing energy in the form of adenosine triphosphate (ATP). As we age, mitochondrial function tends to decline, leading to reduced energy production and increased oxidative stress. This decline is associated with various age-related diseases, including neurodegenerative disorders and metabolic syndromes.
By promoting the clearance of dysfunctional mitochondria, Urolithin A helps to maintain a healthy population of mitochondria within cells, thereby supporting overall cellular energy metabolism. This process is particularly important in muscle cells, where energy demand is high. Studies have indicated that Urolithin A supplementation can improve muscle strength and endurance, making it a potential candidate for enhancing physical performance and combating age-related muscle loss, known as sarcopenia.
Chronic inflammation is a hallmark of many age-related diseases, and reducing inflammation can have a positive impact on overall health. Urolithin A appears to modulate inflammatory pathways, potentially lowering the risk of conditions such as cardiovascular disease and certain cancers. By mitigating inflammation, Urolithin A may contribute to improved longevity and a better quality of life as individuals age.
Some research suggests that it may help protect neurons from damage and support cognitive function. This is particularly relevant in the context of neurodegenerative diseases like Alzheimer’s and Parkinson’s, where mitochondrial dysfunction and inflammation play critical roles in disease progression. By promoting mitochondrial health and reducing inflammation, Urolithin A may offer a multifaceted approach to supporting brain health.
All of the benefits of urolithin A stem from how it optimizes mitochondrial health. Mitochondria are key to how everything in your body functions better. They break down glucose and fatty acids from the food you eat into smaller molecules, which triggers the process of producing ATP (cellular energy).
Over time, those hard-working mitochondria become worn and damaged, which reduces their efficiency. Old mitochondria also produce harmful substances that damage DNA proteins and cause oxidative stress, which contributes to aging and disease.
Cells can recognize and mark poorly functioning mitochondria, triggering structures called autophagosomes to surround them and transport them to lysosomes. Here, they are broken down and reused to create new, healthy mitochondria. The entire process is called mitophagy.
Urolithin A stimulates mitophagy, which is of particular interest to researchers because as we age, mitophagy begins to slow, making cells less efficient at functioning. As we age, decreased cellular function means less energy, more fatigue and inflammation, and a higher risk of age-related diseases such as joint problems, Alzheimer's disease and heart disease.
However, dietary and lifestyle changes can help, including physical exercise and a diet rich in antioxidants low in processed foods. Increasing urolithin A levels is another way to enhance cellular function by optimizing mitochondrial health.
May Optimize Muscle Function and Strength
A study in adolescents aged 40 to 65 found that urolithin A increased muscle strength by about 12% compared to a placebo and improved several biomarkers of mitochondrial health. The researchers believe that with urolithin A, the mitochondria in muscle cells can work more efficiently, meaning they can work harder and longer, so you can get better results from strength training and slow down age-related strength loss.
Memory and cognitive function
The same study on muscle strength also found that urolithin A can reduce inflammation levels. Older, damaged mitochondria produce harmful substances that cause inflammation, so effectively destroying mitochondria with the support of urolithin A can help control inflammation levels.
Supports cardiovascular health
Your heart is a muscle that requires a lot of energy to function properly, so the healthier your mitochondria are, the better. Research has also shown that consuming urolithin A can strengthen blood vessel function, possibly by increasing bacteria that produce helpful compounds associated with vascular health.
Memory and recognition
Another energy-hungry organ is your brain. More efficient, healthier mitochondria are better able to power your brain and don’t release substances that cause inflammation. Lowering inflammation levels in the brain can help ward off age-related cognitive decline and diseases like Alzheimer’s.
Memory and healthy skin
●Emerging evidence suggests that urolithin A has the potential to support healthy skin in multiple ways.
●It can promote the production of collagen, making the skin tighter and smoother.
●Protects against oxidative stress that causes skin aging.
●May encourage autophagy, allowing new cells to form and healthier-looking skin.
● May promote better and faster cell rejuvenation during wound healing
Urolithin A is a natural postbiotic compound that is produced in the gut when ellagitannin-rich foods such as pomegranates, berries and nuts are consumed. It supports mitochondrial health and benefits muscle function as well as brain, heart and skin health. However, not everyone produces urolithin A naturally, leading some to use supplements to take advantage of its potential benefits for energy production and overall cellular health.
Urolithin A is a compound produced by intestinal microorganisms after metabolizing certain plant compounds (such as tannic acid). It has attracted much attention for its potential benefits in anti-aging, improving mitochondrial function and promoting cell autophagy. In order to meet the market demand for high-quality Urolithin A, it is particularly important to choose a reliable supplier.
Suzhou Myland Nutraceuticals Inc. is a company specializing in the research and development and production of dietary supplements, committed to providing customers with high-purity Urolithin A. The product's CAS number is 1143-70-0, and its purity is as high as 98%, ensuring its reliability and effectiveness in various applications.
Features
High purity: Myland Nutraceuticals' Urolithin A is 98% pure, which means users can get more accurate and consistent results during use. High-purity products can effectively reduce the impact of impurities on the body and ensure the safety and effectiveness of supplements.
Quality Assurance: As an experienced biotechnology company, Myland Nutraceuticals strictly follows international standards for production and quality control. Each batch of products undergoes rigorous testing to ensure that they meet relevant quality standards. Customers can use them with confidence and reduce the risk of product quality issues.
Wide Application: Urolithin A has a wide range of applications in health products, nutritional supplements and basic research. It can not only be used as a nutritional supplement, but also can be used to improve cell function and promote health.
Where to buy
Myland Nutraceuticals provides a convenient online purchasing channel. Customers can place orders directly through the official website and enjoy fast logistics services. In addition, the company's professional team will also provide customers with technical support and consulting services to help customers better understand and use the products.
In conclusion
When looking for high-quality Urolithin A, Myland Nutraceuticals is undoubtedly a trustworthy choice. With its high purity, strict quality control and wide application prospects, Myland Nutraceuticals' products can meet the various needs of researchers and companies. Whether conducting basic research or developing new products, choosing Myland Nutraceuticals' Urolithin A will give you high-quality protection and support.
Disclaimer: This article is for general information only and should not be construed as any medical advice. Some of the blog post information comes from the Internet and is not professional. This website is only responsible for sorting, formatting and editing articles. The purpose of conveying more information does not mean that you agree with its views or confirm the authenticity of its content. Always consult a health care professional before using any supplements or making changes to your health care regimen.
Post time: Jan-08-2025
